We show that the temperature dependences of the basal-plane electrical resistance in cuprates of the 1–2–3 system can be described as a consequence of scattering of charge carriers on phonons and defects in conjunction with the fluctuation conductivity. The electron–phonon parameters values deduced from fitting the experimental data to recognized models are close to those for metallic alloys of complex composition. It is revealed that at a large oxygen deficit (lowsuperconducting transition temperatures Tc), the superconducting behavior of the studied cuprates has similarities with that of complex superconducting alloys. At the optimum oxygen deficit (maximal Tcs), superconductivity in the investigated cuprates is likely governed by some other mechanisms.